[利奥多昔对实验性眼部感染中单纯疱疹病毒形态发生的影响]
[Effect of riodoxol on herpes simplex virus morphogenesis in experimental eye infection].
作者信息
Stebaeva L F, Nikolaeva I S, Pershin G N
出版信息
Vopr Virusol. 1982 Jan-Feb(1):90-4.
PMID:6280397
Abstract
The effect of riodoxol on herpes simplex type 1 viruses was studied. It was shown to affect multiplication and maturation of the virus as manifested in the appearance of virions with incomplete nucleoid structure and long-term presence of virions in cytoplasmic vacuoles in cells. Submicroscopic changes suggest a dual effect of riodoxol on herpes simplex virus: on the DNA replicative cycle and on the stage of late maturation of virus at the time of its release from the nucleus.'
摘要
研究了利奥多索对1型单纯疱疹病毒的作用。结果表明，它会影响病毒的增殖和成熟，表现为出现核仁结构不完整的病毒粒子以及病毒粒子在细胞胞质空泡中的长期存在。亚微观变化表明利奥多索对单纯疱疹病毒有双重作用：对DNA复制周期以及病毒从细胞核释放时的晚期成熟阶段都有影响。
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