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泪腺腺样囊性癌:基底样组织学模式的临床意义

Adenoid cystic carcinoma of the lacrimal gland: the clinical significance of a basaloid histologic pattern.

作者信息

Gamel J W, Font R L

出版信息

Hum Pathol. 1982 Mar;13(3):219-25. doi: 10.1016/s0046-8177(82)80180-9.

DOI:10.1016/s0046-8177(82)80180-9
PMID:6281163
Abstract

The authors reviewed 74 adenoid cystic carcinomas of the lacrimal gland, 54 of which had sufficient follow-up data for analysis of survival. Patients with a basaloid pattern in their tumor had a five-year survival rate of 21 per cent and a median survival of three years, whereas patients whose tumor contained no trace of a basaloid component had a five-year survival rate of 71 per cent and a median survival rate of eight years. Nonparametric statistical analysis revealed that this difference in survival was significant at the 0.0005 level. The authors propose that, in the future, pathologists label all adenoid cystic carcinomas as either "basaloid" or "nonbasaloid" and code each case accordingly.

摘要

作者回顾了74例泪腺腺样囊性癌,其中54例有足够的随访数据用于生存分析。肿瘤具有基底样模式的患者五年生存率为21%,中位生存期为三年,而肿瘤无基底样成分痕迹的患者五年生存率为71%,中位生存期为八年。非参数统计分析显示,这种生存差异在0.0005水平上具有显著性。作者建议,未来病理学家应将所有腺样囊性癌标记为“基底样”或“非基底样”,并相应地对每个病例进行编码。

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