大肠杆菌的tolC基因座影响三种主要外膜蛋白的表达。
The tolC locus of Escherichia coli affects the expression of three major outer membrane proteins.
作者信息
Morona R, Reeves P
出版信息
J Bacteriol. 1982 Jun;150(3):1016-23. doi: 10.1128/jb.150.3.1016-1023.1982.
Abstract
tolC mutants, which are resistant to colicin E1 and also highly sensitive to detergents and dyes, were shown to lack the OmpF outer membrane protein. There was little effect on transcription as judged by the use of an ompF-lac operon fusion strain, and the tolC effect was probably due to a post-transcriptional effect. The NmpC protein and protein 2 were also tolC dependent.
摘要
tolC突变体对大肠杆菌素E1具有抗性，同时对去污剂和染料高度敏感，研究表明其缺乏外膜蛋白OmpF。通过使用ompF - lac操纵子融合菌株判断，对转录几乎没有影响，tolC的作用可能是由于转录后效应。NmpC蛋白和蛋白2也依赖于tolC。
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