Bernard K W, Hierholzer J C, Dugan J B, DeLay P R, Helmick C G
Am J Trop Med Hyg. 1982 May;31(3 Pt 1):541-7. doi: 10.4269/ajtmh.1982.31.541.
During July-September 1980, an epidemic of acute hemorrhagic conjunctivitis (AHC) occurred in several refugee camps and transit centers in Southeast Asia. Of 2,356 refugees examined in Bangkok, 200 (8.5%) had conjunctivitis, including 116 (58%) with hemorrhagic signs. Because increasing numbers of refugees were arriving in the United States with conjunctivitis, a program of surveillance and control was implemented. Enterovirus 70, not previously reported from patients in the Western Hemisphere, was cultured from four arriving refugees. A fourfold rise in titer to enterovirus 70 was found in 10 others, either in the United States or Thailand. After control measures were instituted, the prevalence of the United States or Thailand. After control measures were instituted, the prevalence of conjunctivitis in arriving refugees declined from 49.8 per 1,000 to 3.8 per 1,000. Follow-up of cases after arrival in the United States revealed only one possible secondary case. Extensive epidemics of AHC in the Western Hemisphere are most likely to occur following importation into the humid, coastal areas of Central and South America.
1980年7月至9月期间，东南亚的几个难民营和中转中心爆发了急性出血性结膜炎（AHC）疫情。在曼谷接受检查的2356名难民中，200人（8.5%）患有结膜炎，其中116人（58%）有出血症状。由于越来越多患有结膜炎的难民抵达美国，因此实施了一项监测和控制计划。从四名抵达的难民身上培养出了此前在西半球患者中未报告过的肠道病毒70型。在美国或泰国，另外10人的肠道病毒70型抗体滴度呈四倍增长。采取控制措施后，抵达难民中结膜炎的患病率从每1000人49.8例降至每1000人3.8例。对抵达美国后的病例进行随访发现，只有一例可能的二代病例。AHC在西半球的大规模流行最有可能在病毒传入中美洲和南美洲潮湿的沿海地区之后发生。
