Damstra T, Jurgelski W, Posner H S, Vouk V B, Bernheim N J, Guthrie J, Luster M, Falk H L
Environ Health Perspect. 1982 Apr;44:175-88. doi: 10.1289/ehp.8244175.
The composition, environmental fate, and effects of the polybrominated biphenyls (Firemaster BP-6 or FF-1) involved in the accidental contamination of cattle feed in Michigan in 1973 are reviewed. Toxic effects referred to in this report are limited to those occurring in domestic and laboratory animals and include general toxicity, neurobehavioral toxicity, immunotoxicity, reproductive toxicity, mutagenicity and carcinogenicity. The absorption, distribution, biotransformation and elimination of these polybrominated biphenyls are discussed along with the interactions with other chemicals and drugs.
本文回顾了1973年密歇根州牛饲料意外污染事件中涉及的多溴联苯(Firemaster BP - 6或FF - 1)的成分、环境归宿及影响。本报告中提及的毒性作用仅限于在家养动物和实验动物中出现的情况,包括一般毒性、神经行为毒性、免疫毒性、生殖毒性、致突变性和致癌性。文中还讨论了这些多溴联苯的吸收、分布、生物转化和消除情况,以及它们与其他化学品和药物的相互作用。