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铂配合物与金枪鱼细胞色素c的结合。

The binding of platinum complexes to tuna cytochrome c.

作者信息

Boswell A P, Moore G R, Williams R J

出版信息

Biochem J. 1982 Mar 1;201(3):523-6. doi: 10.1042/bj2010523.

Abstract

The binding of [PtCl4]2- and cis-[PtCl2(NH3)2] to methionine-65 of tuna cytochrome c was investigated by 1H n.m.r. The modification at methionine-65 is shown to cause an extremely small structural perturbation to the protein at the site of modification.

摘要

通过氢核磁共振研究了[PtCl4]2-和顺式-[PtCl2(NH3)2]与金枪鱼细胞色素c的蛋氨酸-65的结合情况。结果表明,蛋氨酸-65处的修饰对修饰位点处的蛋白质结构造成的扰动极小。

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本文引用的文献

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Nuclear-magnetic-resonance studies of eukaryotic cytochrome c. Assignment of resonances of aliphatic amino acids.
Eur J Biochem. 1980 Feb;103(3):503-12. doi: 10.1111/j.1432-1033.1980.tb05974.x.
4
The effect of chloroplatinite on the 1H NMR spectrum of ribonuclease. Solvent accessibility of methionine residues.
Biochim Biophys Acta. 1974 Jul 7;359(1):13-21. doi: 10.1016/0005-2795(74)90127-5.

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