对甲硫氨酸-65位点修饰的真核细胞色素c的结构研究。
Structural studies of eukaryotic cytochrome c modified at methionine-65.
作者信息
Boswell A P, Moore G R, Williams R J, Wallace C J, Boon P J, Nivard R J, Tesser G I
出版信息
Biochem J. 1981 Feb 1;193(2):493-502. doi: 10.1042/bj1930493.
Abstract
1H n.m.r. spectra were recorded in both oxidation states for the following species: tuna cytochrome c, tuna [carboxymethylmethionine-65]cytochrome c, horse cytochrome c and horse [homoserine-65]cytochrome c. The experiments give the assignments of the singlet methyl resonances of methionine-65 and the N-terminal acetyl group. The modification at methionine-65 is shown to cause an extremely small structural perturbation to one part of the molecule close to the site of modification.
摘要
记录了以下物种在两种氧化态下的1H核磁共振谱：金枪鱼细胞色素c、金枪鱼[羧甲基甲硫氨酸-65]细胞色素c、马细胞色素c和马[高丝氨酸-65]细胞色素c。实验给出了甲硫氨酸-65的单峰甲基共振和N端乙酰基的归属。结果表明，甲硫氨酸-65处的修饰对分子中靠近修饰位点的一部分结构产生了极小的扰动。
相似文献
1
Structural studies of eukaryotic cytochrome c modified at methionine-65.对甲硫氨酸-65位点修饰的真核细胞色素c的结构研究。
Biochem J. 1981 Feb 1;193(2):493-502. doi: 10.1042/bj1930493.
2
1H NMR studies of eukaryotic cytochrome c. Resonance assignments and iron-hexacyanide-mediated electron exchange.真核细胞色素c的1H NMR研究。共振归属及铁氰化物介导的电子交换。
Eur J Biochem. 1982 May 17;124(2):289-94.
3
Proton hyperfine resonance assignments using the nuclear Overhauser effect for ferric forms of horse and tuna cytochrome c.利用核Overhauser效应进行马和金枪鱼细胞色素c铁形式的质子超精细共振归属
Biophys J. 1987 Jul;52(1):101-7. doi: 10.1016/S0006-3495(87)83193-4.
4
The binding of platinum complexes to tuna cytochrome c.铂配合物与金枪鱼细胞色素c的结合。
Biochem J. 1982 Mar 1;201(3):523-6. doi: 10.1042/bj2010523.
5
Solution structure of mitochondrial cytochrome c. I. 1H nuclear magnetic resonance of ferricytochrome c.线粒体细胞色素c的溶液结构。I. 高铁细胞色素c的1H核磁共振
J Mol Biol. 1985 Jun 5;183(3):409-28. doi: 10.1016/0022-2836(85)90011-7.
6
Solution structure of mitochondrial cytochrome c. II. 1H nuclear magnetic resonance of ferrocytochrome c.线粒体细胞色素c的溶液结构。II. 亚铁细胞色素c的1H核磁共振
J Mol Biol. 1985 Jun 5;183(3):429-46. doi: 10.1016/0022-2836(85)90012-9.
7
Structural role of the tyrosine residues of cytochrome c.细胞色素c中酪氨酸残基的结构作用。
Biochem J. 1982 Jul 1;205(1):153-65. doi: 10.1042/bj2050153.
8
The solution structures of tuna and horse cytochromes c.
Eur J Biochem. 1980 Feb;103(3):533-41. doi: 10.1111/j.1432-1033.1980.tb05977.x.
9
The conformation of eukaryotic cytochrome c around residues 39, 57, 59 and 74.真核细胞色素c在39、57、59和74位残基附近的构象。
Biochem J. 1983 Sep 1;213(3):687-700. doi: 10.1042/bj2130687.
10
Comparison of protein structures in solution using local conformations derived from NMR data: application to cytochrome c.利用源自核磁共振数据的局部构象比较溶液中的蛋白质结构：应用于细胞色素c
J Biomol Struct Dyn. 1994 Dec;12(3):527-58. doi: 10.1080/07391102.1994.10508758.
引用本文的文献
1
The effect of complete or specific partial acetimidylation on the biological properties of cytochrome c and cytochrome c-T.完全或特定部分乙酰亚胺化对细胞色素c和细胞色素c-T生物学特性的影响。
Biochem J. 1984 Feb 1;217(3):595-9. doi: 10.1042/bj2170595.
2
The semisynthesis of analogues of cytochrome c. Modifications of arginine residues 38 and 91.细胞色素c类似物的半合成。精氨酸残基38和91的修饰。
Biochem J. 1983 Dec 1;215(3):651-8. doi: 10.1042/bj2150651.
3
1H-n.m.r. investigation of the interaction between cytochrome c and cytochrome b5.细胞色素c与细胞色素b5相互作用的1H核磁共振研究
Biochem J. 1983 Oct 1;215(1):11-21. doi: 10.1042/bj2150011.
4
Structural role of the tyrosine residues of cytochrome c.细胞色素c中酪氨酸残基的结构作用。
Biochem J. 1982 Jul 1;205(1):153-65. doi: 10.1042/bj2050153.
5
The binding of platinum complexes to tuna cytochrome c.铂配合物与金枪鱼细胞色素c的结合。
Biochem J. 1982 Mar 1;201(3):523-6. doi: 10.1042/bj2010523.
本文引用的文献
1
Nuclear-magnetic-resonance studies of eukaryotic cytochrome c. Assignment of resonances of aliphatic amino acids.
Eur J Biochem. 1980 Feb;103(3):503-12. doi: 10.1111/j.1432-1033.1980.tb05974.x.
2
Nuclear-magnetic-resonance studies of eukaryotic cytochrome c. Assignment of resonances of aromatic amino acids.
Eur J Biochem. 1980 Feb;103(3):493-502. doi: 10.1111/j.1432-1033.1980.tb05973.x.
3
Alkylation of cytochromes c. II. Carboxymethylation of beef and human cytochromes c in the oxidized and reduced forms.
Biochim Biophys Acta. 1966 May 5;118(2):256-67. doi: 10.1016/s0926-6593(66)80034-6.
4
Proton magnetic resonance spectra of proteins in random-coil configurations.随机卷曲构象的蛋白质的质子磁共振谱。
J Am Chem Soc. 1969 Mar 12;91(6):1513-21. doi: 10.1021/ja01034a039.
5
Carboxymethylation of horse heart ferricytochrome c and cyanferricytochrome c.马心脏铁细胞色素c和氰化铁细胞色素c的羧甲基化作用
Biochemistry. 1968 Jul;7(7):2496-501. doi: 10.1021/bi00847a008.
6
Ferricytochrome c. I. General features of the horse and bonito proteins at 2.8 A resolution.高铁细胞色素c。I. 马和鲣鸟蛋白质在2.8埃分辨率下的一般特征。
J Biol Chem. 1971 Mar 10;246(5):1511-35.
7
Reconstitution of horse heart cytochrome c: reformation of the peptide bond linking residues 65 and 66.马心脏细胞色素c的复性：连接65和66位残基的肽键的重新形成。
Biochem Biophys Res Commun. 1974 Dec 23;61(4):1400-6. doi: 10.1016/s0006-291x(74)80439-0.
8
Proton magnetic resonance studies of horse cytochrome c.马细胞色素c的质子磁共振研究。
Biochemistry. 1973 Aug 14;12(17):3170-86. doi: 10.1021/bi00741a006.
9
Pulsed NMR study of the structure of cytochrome c.细胞色素c结构的脉冲核磁共振研究。
Cold Spring Harb Symp Quant Biol. 1972;36:405-11. doi: 10.1101/sqb.1972.036.01.052.
10
Pulse methods for the simplification of protein NMR spectra.用于简化蛋白质核磁共振谱的脉冲方法。
FEBS Lett. 1975 Sep 1;57(1):96-9. doi: 10.1016/0014-5793(75)80160-8.
Zotero 插件