脾脏原发性恶性纤维组织细胞瘤：超微结构研究

Primary malignant fibrous histiocytoma of the spleen: an ultrastructural study.

作者信息

Govoni E, Bazzocchi F, Pileri S, Martinelli G

出版信息

Histopathology. 1982 May;6(3):351-61. doi: 10.1111/j.1365-2559.1982.tb02729.x.

DOI:10.1111/j.1365-2559.1982.tb02729.x

Abstract

A primary malignant fibrous histiocytoma of the spleen was studied by light and electron microscopy and is believed to be the first reported. The neoplasm was predominantly fibroblastic, with a characteristic storiform pattern, and included histiocyte-like cells, giant and foam cells confirmed by ultrastructural studies. Additionally, undifferentiated cells, intermediate cells and myofibroblasts were seen. The differential diagnosis from other sarcomas and the histogenesis of this tumour are discussed.

摘要

通过光镜和电镜对一例原发性脾脏恶性纤维组织细胞瘤进行了研究，据信这是首次报道。该肿瘤主要为成纤维细胞性，具有特征性的席纹状结构，超微结构研究证实其中包括组织细胞样细胞、巨细胞和泡沫细胞。此外，还可见未分化细胞、中间细胞和成肌纤维细胞。讨论了与其他肉瘤的鉴别诊断及该肿瘤的组织发生。