Hoffman M A, Dickersin G R
Hum Pathol. 1983 Oct;14(10):913-22. doi: 10.1016/s0046-8177(83)80166-x.
Eleven cases of malignant fibrous histiocytoma were examined electron microscopically. In six of seven cases with storiform-fascicular histologic features and in two cases with a myxoid pattern, no malignant-appearing histiocyte-like cells were identified. The neoplastic cells were fibroblasts and myofibroblasts, occasionally admixed with lymphocytes and benign-appearing histiocytes. Only in the other three cases (two pleomorphic sarcomas and one tumor with a storiform-fascicular pattern) were malignant cells with the features of histiocytes identified. The authors propose that some neoplasms with a storiform-fascicular pattern would be more accurately classified as fibrosarcomas than as histiocytomas and speculate on the possible histogenesis of those tumors that do contain histiocyte-type cells.
对11例恶性纤维组织细胞瘤进行了电子显微镜检查。在7例具有席纹状-束状组织学特征的病例中的6例以及2例具有黏液样模式的病例中，未发现具有恶性特征的组织细胞样细胞。肿瘤细胞为成纤维细胞和肌成纤维细胞，偶尔混有淋巴细胞和外观良性的组织细胞。仅在其他3例（2例多形性肉瘤和1例具有席纹状-束状模式的肿瘤）中发现了具有组织细胞特征的恶性细胞。作者提出，一些具有席纹状-束状模式的肿瘤更准确地应归类为纤维肉瘤而非组织细胞瘤，并推测了那些确实含有组织细胞型细胞的肿瘤的可能组织发生。
