百日咳博德特氏菌促淋巴细胞增多因子对小脑环磷酸鸟苷水平的影响。
Effect of lymphocytosis-promoting factor from Bordetella pertussis on cerebellar cyclic GMP levels.
作者信息
Askelöf P, Gillenius P
出版信息
Infect Immun. 1982 Jun;36(3):958-61. doi: 10.1128/iai.36.3.958-961.1982.
Abstract
Dermonecrotic toxin (DNT), lipopolysaccharide (LPS), and lymphocytosis-promoting factor (LPF) were isolated from Bordetella pertussis and tested for neuroactivity. When injected intraperitoneally into rats, a dose of 0.13 mg of LPF per kg elevated the cyclic GMP level in cerebellum by approximately 70%, whereas DNT (0.5 mg/kg) and LPS (1.5 mg/kg) were without effect. This action of LPF on the central nervous system was dose dependent and did not require the administration of any additional agent, such as histamine.
摘要
从百日咳博德特氏菌中分离出皮肤坏死毒素（DNT）、脂多糖（LPS）和淋巴细胞增多促进因子（LPF），并对其神经活性进行了测试。当以每千克0.13毫克的剂量腹腔注射到大鼠体内时，LPF可使小脑环磷酸鸟苷水平升高约70%，而DNT（0.5毫克/千克）和LPS（1.5毫克/千克）则无此作用。LPF对中枢神经系统的这种作用具有剂量依赖性，并且不需要施用任何其他药剂，如组胺。
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本文引用的文献
1
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Am J Public Health Nations Health. 1946 Apr;36(4):371-6.
2
A colorimetric method for the determination of sugars.一种测定糖类的比色法。
Nature. 1951 Jul 28;168(4265):167. doi: 10.1038/168167a0.
3
Pertussis immunisation and serious acute neurological illness in children.儿童百日咳免疫接种与严重急性神经系统疾病
Br Med J (Clin Res Ed). 1981 May 16;282(6276):1595-9. doi: 10.1136/bmj.282.6276.1595.
4
Purification and characterisation of a fimbrial haemagglutinin from Bordetella pertussis for use in an enzyme-linked immunosorbent assay.用于酶联免疫吸附测定的百日咳博德特氏菌菌毛血凝素的纯化与特性鉴定
J Med Microbiol. 1982 Feb;15(1):73-83. doi: 10.1099/00222615-15-1-73.
5
Biological activities of crystalline pertussigen from Bordetella pertussis.百日咳博德特氏菌结晶性百日咳毒素的生物学活性
Infect Immun. 1981 Sep;33(3):820-6. doi: 10.1128/iai.33.3.820-826.1981.
6
Bordetella pertussis respiratory tract infection in the mouse: pathophysiological responses.小鼠百日咳博德特氏菌呼吸道感染：病理生理反应
J Infect Dis. 1980 Jul;142(1):56-66. doi: 10.1093/infdis/142.1.56.
7
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8
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9
10
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