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正常月经周期。子宫内膜剥脱的时间顺序及机制。

The normal menstrual cycle. Chronology and mechanism of endometrial desquamation.

作者信息

Nogales-Ortiz F, Puerta J, Nogales F F

出版信息

Obstet Gynecol. 1978 Mar;51(3):259-64. doi: 10.1097/00006250-197803000-00001.

DOI:10.1097/00006250-197803000-00001
PMID:628526
Abstract

Morphologic studies were performed on 25 uteri obtained at different times during the menstrual cycle, ranging from 2 to 140 hours following the onset of menstruation. The amount of endometrium desquamated varied; usually only the more superficial parts--the compacta layer and small areas of the spongiosa--were shed, but in some instances desquamation extended almost to the muscularis. The remaining spongiosa, depleted and shrunken, is misleading in its appearance, resembling a basalis layer. Actually, such a layer appears morphologically distinct only during the initial parts of the cycle and undergoes secretory changes at the same rate as the rest of the endometrium. Desquamation and regeneration coexist, desquamation appearing almost complete by 60 hours, whereas regenerating epithelium is seen as early as 36 hours. Complete regeneration takes place by 140 hours after the initiation of menstruation.

摘要

对在月经周期不同时间获取的25个子宫进行了形态学研究,时间范围为月经开始后2至140小时。脱落的子宫内膜量各不相同;通常仅较浅的部分——致密层和海绵层的小区域——会脱落,但在某些情况下,脱屑几乎延伸至肌层。剩余的海绵层,变薄且萎缩,其外观具有误导性,类似于基底层。实际上,这样的一层仅在周期的初始阶段在形态上明显不同,并与子宫内膜的其余部分以相同速度经历分泌变化。脱屑和再生同时存在,脱屑在60小时时几乎完成,而再生上皮最早在36小时时可见。月经开始后140小时完成完全再生。

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The normal menstrual cycle. Chronology and mechanism of endometrial desquamation.正常月经周期。子宫内膜剥脱的时间顺序及机制。
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