Suppr超能文献

根据DNA限制性酶切图谱估计系统发育关系及选择核酸内切酶切割位点

Estimation of phylogenetic relationships from DNA restriction patterns and selection of endonuclease cleavage sites.

作者信息

Adams J, Rothman E D

出版信息

Proc Natl Acad Sci U S A. 1982 Jun;79(11):3560-4. doi: 10.1073/pnas.79.11.3560.

Abstract

The distribution of cleavage sites and their related sequences have been analyzed for 54 restriction endonucleases in the genome of human mitochondrial DNA; in three papova viruses, BK, simian virus 40, and polyoma; and in three bacteriophages, phi X174, fd, and G4. The results show that the cleavage sites and related sequences for most of the restriction enzymes tested are distributed nonrandomly. These results (i) constitute prima facie evidence for the action of natural selection, either direct or indirect on the restriction sites, and (ii) suggest that estimates of phylogenetic relationship, based on a phenetic approach using restriction enzyme data, will be biased.

摘要

已对人类线粒体DNA基因组中的54种限制性内切酶、三种乳头瘤病毒(BK病毒、猴病毒40和多瘤病毒)以及三种噬菌体(φX174、fd和G4)的切割位点及其相关序列进行了分析。结果表明,所测试的大多数限制性酶的切割位点和相关序列呈非随机分布。这些结果(i)构成了自然选择对限制位点直接或间接作用的初步证据,(ii)表明基于使用限制酶数据的表型方法对系统发育关系的估计将存在偏差。

相似文献

引用本文的文献

本文引用的文献

1
ON THE TOPOGRAPHY OF THE GENETIC FINE STRUCTURE.论遗传精细结构的拓扑学
Proc Natl Acad Sci U S A. 1961 Mar;47(3):403-15. doi: 10.1073/pnas.47.3.403.
2
Eukaryotic promoters?真核生物启动子?
Nature. 1979 May 31;279(5712):376. doi: 10.1038/279376a0.
4
Codon recognition rules in yeast mitochondria.酵母线粒体中的密码子识别规则。
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3167-70. doi: 10.1073/pnas.77.6.3167.
10

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验