环磷酸腺苷与犬胃酸分泌
Cyclic AMP and gastric acid secretion in the dog.
作者信息
Hall J C, Jerums G, Douglas M C
出版信息
Aust N Z J Surg. 1982 Jun;52(3):275-7. doi: 10.1111/j.1445-2197.1982.tb05401.x.
Abstract
Canine gastric secretions were collected for acid and cyclic AMP assay at zero, 15, 30, 45 and 60 minutes during intravenous infusion of zero, 2.5 and 5.0 micrograms/kg/hr of pentagastrin. A resulting brisk acid response was not accompanied by an elevation of cyclic AMP content. It is thereby suggested that cyclic AMP may not be an obligatory intermediary for gastric acid secretion.
摘要
在静脉输注0、2.5和5.0微克/千克/小时的五肽胃泌素期间，分别在0、15、30、45和60分钟时收集犬的胃分泌物，用于酸和环磷酸腺苷（cAMP）测定。结果产生的强烈酸反应并未伴随着环磷酸腺苷含量的升高。由此表明，环磷酸腺苷可能不是胃酸分泌的必需中间介质。
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