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包涵体肌炎。临床、生物学及超微结构研究。

Inclusion body myositis. Clinical, biological and ultrastructural study.

作者信息

Julien J, Vital C, Vallat J M, Lagueny A, Sapina D

出版信息

J Neurol Sci. 1982 Jul;55(1):15-24. doi: 10.1016/0022-510x(82)90166-6.

DOI:10.1016/0022-510x(82)90166-6
PMID:6286889
Abstract

A 48-year-old patient presented for the past 4 years an amyotrophy of the quadriceps and moderate involvement of the truncal and pelvic girdle muscles. The CK level was elevated (10 times the normal rate) and the EMG revealed a fibrillation pattern on relaxation, myotonic bursts on needle insertion and reduced activity during contraction. The histological study of the muscle biopsy showed nuclear cytoplasmic inclusion bodies and pseudo-myelinic membranes. The case was classified in the inclusion body myositis group. Analysis of the other published cases underlines the variety of the clinical, biological and electromyographical aspects and abnormalities.

摘要

一名48岁患者在过去4年中出现股四头肌萎缩,躯干和骨盆带肌肉中度受累。肌酸激酶(CK)水平升高(为正常水平的10倍),肌电图显示静息时出现纤颤电位,针电极插入时出现肌强直放电,收缩时活动减弱。肌肉活检的组织学研究显示有核内胞质包涵体和假髓鞘膜。该病例被归类为包涵体肌炎组。对其他已发表病例的分析强调了临床、生物学和肌电图方面及异常情况的多样性。

相似文献

1
Inclusion body myositis. Clinical, biological and ultrastructural study.包涵体肌炎。临床、生物学及超微结构研究。
J Neurol Sci. 1982 Jul;55(1):15-24. doi: 10.1016/0022-510x(82)90166-6.
2
Inclusion body myositis in post-poliomyelitis muscular atrophy.脊髓灰质炎后肌肉萎缩中的包涵体肌炎
Acta Neurol Scand. 1988 Aug;78(2):81-4. doi: 10.1111/j.1600-0404.1988.tb03625.x.
3
[Electromyographic aspects of inclusion body myositis. Macro-electromyographic study].[包涵体肌炎的肌电图表现。宏观肌电图研究]
Rev Electroencephalogr Neurophysiol Clin. 1987 Sep;17(3):319-28. doi: 10.1016/s0370-4475(87)80069-2.
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Inclusion body myositis with abundant ring fibers.伴有大量镶边纤维的包涵体肌炎
Acta Neuropathol. 1992;85(1):105-10. doi: 10.1007/BF00304640.
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Inclusion body myositis: case reports and a reappraisal of an underrecognized type of inflammatory myopathy.包涵体肌炎:病例报告及对一种未被充分认识的炎性肌病类型的重新评估。
Mt Sinai J Med. 1986 Feb;53(2):137-44.
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Inclusion body myositis: a case with associated collagen vascular disease responding to treatment.包涵体肌炎:1例合并胶原血管病且治疗有效的病例。
J Neurol Neurosurg Psychiatry. 1985 Mar;48(3):270-3. doi: 10.1136/jnnp.48.3.270.
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Inclusion body myositis.包涵体肌炎
Acta Neuropathol Suppl. 1981;7:287-91. doi: 10.1007/978-3-642-81553-9_83.
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[Inclusion-body myositis: a familial report of 3 cases].[包涵体肌炎:3例家族性报告]
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Clinically unsuspected inclusion body myositis.临床未怀疑的包涵体肌炎
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[Inclusion body myositis: its clinico-electrophysiological and morphological diagnosis].[包涵体肌炎:其临床电生理及形态学诊断]
Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(2):71-6.

引用本文的文献

1
Inclusion body myositis: clinical and histopathological features of 36 patients.
Clin Investig. 1993 May;71(5):351-61. doi: 10.1007/BF00186623.
2
Inclusion body myositis: a case with associated collagen vascular disease responding to treatment.包涵体肌炎:1例合并胶原血管病且治疗有效的病例。
J Neurol Neurosurg Psychiatry. 1985 Mar;48(3):270-3. doi: 10.1136/jnnp.48.3.270.
3
Inflammatory and non-inflammatory inclusion body myositis. Characterization of the mononuclear cells and expression of the immunoreactive class I major histocompatibility complex product.炎性和非炎性包涵体肌炎。单核细胞的特征及免疫反应性I类主要组织相容性复合体产物的表达。
Acta Neuropathol. 1990;79(5):528-36. doi: 10.1007/BF00296113.
4
Inclusion body myositis with abundant ring fibers.伴有大量镶边纤维的包涵体肌炎
Acta Neuropathol. 1992;85(1):105-10. doi: 10.1007/BF00304640.