传染性单核细胞增多症脑炎患者脑脊液中的爱泼斯坦-巴尔病毒
Epstein-Barr virus in cerebrospinal fluid during infectious mononucleosis encephalitis.
作者信息
Schiff J A, Schaefer J A, Robinson J E
出版信息
Yale J Biol Med. 1982 Jan-Feb;55(1):59-63.
Abstract
Epstein-Barr virus (EBV) was recovered from cerebrospinal cells (but not from cell-free fluid) of a patient with meningoencephalitis complicating infectious mononucleosis. This finding suggests that virus-altered B lymphocytes can invade the central nervous system and may play a direct role in the pathogenesis of neurologic sequelae of EBV infections. Several mechanisms by which these cells can cause neurologic manifestations are discussed.
摘要
从一名患有传染性单核细胞增多症并发脑膜脑炎患者的脑脊液细胞（而非无细胞液）中分离出了爱泼斯坦-巴尔病毒（EBV）。这一发现表明，病毒改变的B淋巴细胞可侵入中枢神经系统，并可能在EBV感染的神经后遗症发病机制中起直接作用。文中讨论了这些细胞导致神经表现的几种机制。
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