Belasco J B, Meadows A T, Chatten J, Borden S, Schnaufer L
Cancer. 1982 Nov 1;50(9):1894-8. doi: 10.1002/1097-0142(19821101)50:9<1894::aid-cncr2820500941>3.0.co;2-s.
A large proportion of children with Wilms' tumor will become long-term disease-free survivors. A small number of these children are at risk of developing second malignant neoplasms. There have been no previous reports of osteogenic sarcoma of the chest wall following treatment of Wilms' tumor. Our patient was age seven years when he received surgery, radiation therapy and chemotherapy for Wilms' tumor, eight years when he received radiation and chemotherapy for pulmonary metastases of Wilms' tumor, and 13 years when he developed osteogenic sarcoma of the chest wall.
大部分患有肾母细胞瘤的儿童将成为长期无病生存者。其中一小部分儿童有发生第二种恶性肿瘤的风险。此前尚无肾母细胞瘤治疗后发生胸壁骨肉瘤的报道。我们的患者在7岁时接受了肾母细胞瘤的手术、放疗和化疗，8岁时接受了肾母细胞瘤肺转移的放疗和化疗，13岁时发生了胸壁骨肉瘤。
