转座子Tn10为相邻序列的转录提供启动子。
Transposon Tn10 provides a promoter for transcription of adjacent sequences.
作者信息
Ciampi M S, Schmid M B, Roth J R
出版信息
Proc Natl Acad Sci U S A. 1982 Aug;79(16):5016-20. doi: 10.1073/pnas.79.16.5016.
Abstract
Promoters located within the Tn10 insertion element cause transcription of "host" sequences adjacent to both ends of the inserted Tn10 element. These promoters are usually not observed in genetic experiments because their transcripts are efficiently terminated at nearby rho-dependent termination sites. The observations presented here provide an explanation for several confusing aspects of transposon behavior and suggest the possibility that many transposons possess promoters that have escaped detection for similar reasons.
摘要
位于Tn10插入元件内的启动子会导致与插入的Tn10元件两端相邻的“宿主”序列发生转录。在遗传实验中通常观察不到这些启动子，因为它们的转录本会在附近的ρ依赖性终止位点高效终止。本文所呈现的观察结果为转座子行为的几个令人困惑的方面提供了解释，并暗示了许多转座子可能拥有因类似原因而未被检测到的启动子的可能性。
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