Knowles W A, Gardner S D, Fox H
Arch Virol. 1982;73(1):25-31. doi: 10.1007/BF01341724.
CMV was isolated from the cervix of 4.2 per cent of 191 gynaecological patients and from 9.8 per cent of 51 women post-partum; all patients were attending the same general practice clinic. The CMV excretion rate was particularly high in the early post-partum period decreasing to nearly normal levels as menstruation returned. Three of 14 (21.4 per cent) post-partum patients excreted CMV before menses had restarted whereas virus was isolated from only two of 36 (5.6 per cent) women who had returned to a normal menstrual cycle. Although this difference was not statistically significant, the excretion rate early post-partum was significantly higher than in the gynaecological group (p less than 0.05). Five of seven excretors in the gynaecological group were in the first half of a menstrual cycle at the time of virus isolation thus suggesting that hormonal changes may lead to CMV reactivation in the genital tract. Other factors which may influence the presence of CMV in the genital tract of non-pregnant women are discussed. Three of four infant born to women excreting virus on the cervix post-partum became infected with CMV.
从191名妇科患者的宫颈中分离出巨细胞病毒（CMV）的比例为4.2%，从51名产后妇女的宫颈中分离出该病毒的比例为9.8%；所有患者均在同一家普通诊所就诊。产后早期CMV排泄率特别高，随着月经恢复，排泄率降至接近正常水平。14名产后患者中有3名（21.4%）在月经恢复前就排出了CMV，而在36名月经周期已恢复正常的妇女中，只有2名（5.6%）分离出了病毒。虽然这种差异无统计学意义，但产后早期的排泄率明显高于妇科组（p<0.05）。妇科组7名病毒排泄者中有5名在病毒分离时处于月经周期的前半期，这表明激素变化可能导致生殖道中CMV重新激活。文中还讨论了可能影响非孕妇生殖道中CMV存在的其他因素。4名产后宫颈排出病毒的妇女所生的婴儿中有3名感染了CMV。
