Clapp J F
Am J Obstet Gynecol. 1978 Feb 15;130(4):419-23. doi: 10.1016/0002-9378(78)90283-1.
Fifteen pregnant ewes were studied to determine what fractions of the increases in maternal cardiac output and oxygen consumption found in pregnancy were due to the concomitant increases in blood flow to and oxygen consumption of the uterus and its tissue contents. Maternal cardiac output rose at term to 6.65 +/- 0.47 L. per minute, a value 40 per cent above the postpartum level. Uterine blood flow, which had increased at term to 1.62 +/- 0.15 L. per minute, represented 24 per cent of maternal cardiac output above postpartum levels. Maternal oxygen consumption at term was 259 +/- 11 c.c. per minute, a value 33 per cent above the postpartum level. Uterine oxygen consumption, which had increased at term to 57 +/- 4 c.c. per minute, represented 22 per cent of maternal oxygen consumption and accounted for 87 per cent of the increase in maternal cardiac output above postpartum levels. These data indicate that in the ewe most of the pregnancy-associated increases in maternal cardiac output and oxygen consumption are due to the demands of the uterus and its tissue contents.
对15只怀孕母羊进行了研究，以确定孕期母体心输出量和耗氧量增加的部分中，有多少是由于子宫及其组织内容物的血流量和耗氧量同时增加所致。足月时母体心输出量升至6.65±0.47升/分钟，比产后水平高40%。子宫血流量在足月时增加到1.62±0.15升/分钟，占产后水平以上母体心输出量的24%。足月时母体耗氧量为259±11毫升/分钟，比产后水平高33%。子宫耗氧量在足月时增加到57±4毫升/分钟，占母体耗氧量的22%，占产后水平以上母体心输出量增加的87%。这些数据表明，在母羊中，孕期母体心输出量和耗氧量的大部分增加是由于子宫及其组织内容物的需求。
