大鼠免疫球蛋白E重链的结构与进化
Structure and evolution of the heavy chain from rat immunoglobulin E.
作者信息
Hellman L, Pettersson U, Engström A, Karlsson T, Bennich H
出版信息
Nucleic Acids Res. 1982 Oct 11;10(19):6041-9. doi: 10.1093/nar/10.19.6041.
Abstract
The nucleotide sequence of the rat epsilon-chain mRNA has been determined by sequencing cloned cDNA copies of the mRNA. The established sequence covers the coding region, the 3'-non coding region and most of the 5' non-coding region. A comparison with the nucleotide sequence of the human epsilon-chain constant region reveals that C3 and C4 are the most highly conserved domains. The rat epsilon-chain contains a C-terminal decapeptide which is not present in the human counterpart.
摘要
通过对大鼠ε链mRNA的克隆cDNA拷贝进行测序，已确定了其核苷酸序列。所确定的序列涵盖了编码区、3'-非编码区和大部分5'-非编码区。与人类ε链恒定区的核苷酸序列比较表明，C3和C4是最保守的结构域。大鼠ε链含有一个C末端十肽，而在人类对应物中不存在。
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本文引用的文献
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