Kern W H
Am J Clin Pathol. 1982 Dec;78(6):847-9. doi: 10.1093/ajcp/78.6.847.
The cytopathologic findings of 196 cases of cancer of the breast were correlated with the hormonal receptor levels. The strict cytologic criteria that allow a positive diagnosis to be used as bases for definitive treatment include adequate cellularity, lack of cohesion, and nuclear abnormalities, including increased nuclear size. On this basis, 58% of the carcinomas of the breast, including 62% of the 157 infiltrating duct carcinomas but none of 12 infiltrating lobular carcinomas, could be diagnosed by aspiration smears alone. Seventy-four per cent of the carcinomas were estrogen-receptor-positive. No correlation could be demonstrated between the cytologic pattern and diagnosis and the level of estrogen, progesterone, or androgen receptors, alone or in any combination.
196例乳腺癌的细胞病理学检查结果与激素受体水平相关。允许将阳性诊断用作确定性治疗依据的严格细胞学标准包括足够的细胞数量、细胞间缺乏黏附以及核异常，包括核增大。在此基础上，58%的乳腺癌，包括157例浸润性导管癌中的62%，但12例浸润性小叶癌中无一例，仅通过细针穿刺涂片即可诊断。74%的癌雌激素受体呈阳性。单独或任何组合的雌激素、孕激素或雄激素受体水平与细胞学模式及诊断之间均未显示出相关性。
