Schneider D R, Felt B T, Rappaport M S, Goldman H
J Pharmacol Methods. 1982 Dec;8(4):265-74. doi: 10.1016/0160-5402(82)90043-2.
The use of microwave energy for rapid killing of small rodents such as the mouse or rat has become a standard pharmacologic technique since approximately 1975. This method allows investigation of rapidly modulated neurochemical indices, neuromodulatory substances, and some neurotransmitters to be determined at basal concentrations in brain regions and microregions. Previously described devices for use with microwave generators have relied on total body restraining holders in order to properly position rodents and neonates within a closed waveguide during microwave energy exposures. The present information describes two alternate chamber designs which do not require restraint of the rodent. A positioning device is described which must be used with the waveguide chambers. The animal chambers are designed to be used with 2450 MHz energy.
自1975年左右以来，利用微波能量快速杀死小鼠或大鼠等小型啮齿动物已成为一种标准的药理学技术。这种方法可以在脑区和微区的基础浓度下，对快速调节的神经化学指标、神经调节物质和一些神经递质进行研究测定。先前描述的与微波发生器配合使用的装置，在微波能量照射期间，依靠全身固定架将啮齿动物和新生动物正确放置在封闭的波导内。本文介绍了两种不需要限制啮齿动物的替代腔室设计。还描述了一种必须与波导腔室配合使用的定位装置。动物腔室设计用于2450MHz能量。
