Silvergleid A J, Kott T J
Vox Sang. 1983;44(2):102-5. doi: 10.1111/j.1423-0410.1983.tb04110.x.
561 consecutive O-negative blood donors were tested for the presence of cytomegalovirus (CMV) antibodies using an indirect fluorescent antibody test. 427 (76.1%) donors were CMV antibody positive, while 134 (23.9%) were seronegative. Males (75.1%) and females (78%) did not differ significantly in seropositivity. 17- to 20-year-old males had the lowest frequency of seropositivity (38.5%), though donors in this category represented only 4% of the 561 consecutive donors. The incidence of seropositivity increased consistently with age. Because of the difficulty in confidently generating sufficient CMV-seronegative donors, it is suggested that the exclusive use of frozen-thawed, or washed, leukocyte-poor blood, be evaluated as an alternative.
采用间接荧光抗体试验对561名连续的O型阴性献血者进行巨细胞病毒（CMV）抗体检测。427名（76.1%）献血者CMV抗体呈阳性，而134名（23.9%）为血清阴性。男性（75.1%）和女性（78%）的血清阳性率无显著差异。17至20岁的男性血清阳性率最低（38.5%），不过该年龄段的献血者仅占561名连续献血者的4%。血清阳性率随年龄持续增加。由于难以可靠地获得足够数量的CMV血清阴性献血者，建议评估将仅使用冻融或洗涤的少白细胞血液作为一种替代方案。
