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[肺癌转移的分布。II. 肿瘤组织学的影响]

[Distribution of lung cancer metastases. II. Effect of tumor histology].

作者信息

Barz H, Barz D

出版信息

Arch Geschwulstforsch. 1982;52(7):561-8.

PMID:6299223
Abstract

The various histological types of 1,283 lung cancers show remarkable differences in sex distribution, in mean age at the time of death, in the localization of tumors and duration of cancer disease as well as in their metastatic behaviour. The proportion of the various histological types of lung cancer in ten organs with blood borne metastases has been analysed. Metastases of small cell carcinomas most frequently occur in pancreas, liver, thyroid gland, bone and adrenal, whereas squamous cell carcinomas are found in kidney and heart. Anepidermic squamous cell carcinomas are most frequently seen in brain and large cell carcinomas in the spleen. As already mentioned in the preceding paper, combinations of metastatic affected organs can be seen with special frequencies in all histological types of lung cancer. However, small cell carcinomas provide the most evident findings.

摘要

1283例肺癌的各种组织学类型在性别分布、死亡时的平均年龄、肿瘤定位、癌症病程以及转移行为方面存在显著差异。对有血行转移的十个器官中肺癌各种组织学类型的比例进行了分析。小细胞癌转移最常发生于胰腺、肝脏、甲状腺、骨骼和肾上腺,而鳞状细胞癌转移见于肾脏和心脏。无表皮鳞状细胞癌最常见于脑,大细胞癌转移常见于脾脏。如前文所述,在肺癌的所有组织学类型中,均可观察到特定频率的转移受累器官组合。然而,小细胞癌的表现最为明显。

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[Distribution of lung cancer metastases. II. Effect of tumor histology].[肺癌转移的分布。II. 肿瘤组织学的影响]
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Mechanism of liver-specific metastatic tumor spread in a murine tumor model.小鼠肿瘤模型中肝脏特异性转移性肿瘤扩散的机制
J Cancer Res Clin Oncol. 1988;114(1):47-58. doi: 10.1007/BF00390485.