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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Thurlby P L, Trayhurn P

Br J Nutr. 1978 Mar;39(2):397-402. doi: 10.1079/bjn19780050.

The body compositions of obob and lean (ob+ and ++) mice at 10, 12, 17 and 28 d of age were investigated using a 'cold stress' test to identify the two groups. 2. At each of these ages the obob mice were found to contain significantly more fat than the lean. At 10 d 20% more fat was present and by 17 d the increase was 72%. The obob mice at 28 d contained nearly three times as much fat as the lean. 3. Carcass energy was significantly higher in obob mice at all ages investigated. 4. Other changes in body composition found in the 28 d obob mice, i.e. a reduction in total carcass nitrogen and water content, were already established in the 17-d-old mice but differences at 10 and 12 d were not apparent. 5. The livers of obob mice were significantly heavier than those from lean control mice at 28 d but no differences were detected at the earlier ages. 6. The results are discussed with reference to the early origin of obesity in obob mice.

使用“冷应激”试验对10日龄、12日龄、17日龄和28日龄的obob和瘦型（ob+和++）小鼠的身体组成进行了研究，以区分这两组小鼠。2. 在这些年龄阶段的每个时间点，发现obob小鼠的脂肪含量均显著高于瘦型小鼠。在10日龄时，obob小鼠的脂肪含量多出20%，到17日龄时，这一增幅达到72%。28日龄的obob小鼠的脂肪含量几乎是瘦型小鼠的三倍。3. 在所有研究的年龄阶段，obob小鼠的胴体能量均显著更高。4. 在28日龄的obob小鼠中发现的身体组成的其他变化，即胴体总氮和水分含量的降低，在17日龄的小鼠中就已经出现，但在10日龄和12日龄时差异不明显。5. 28日龄时，obob小鼠的肝脏明显比瘦型对照小鼠的肝脏更重，但在较早年龄阶段未检测到差异。6. 参考obob小鼠肥胖的早期起源对结果进行了讨论。

Thurlby P L, Trayhurn P

Br J Nutr. 1978 Mar;39(2):397-402. doi: 10.1079/bjn19780050.

The body compositions of obob and lean (ob+ and ++) mice at 10, 12, 17 and 28 d of age were investigated using a 'cold stress' test to identify the two groups. 2. At each of these ages the obob mice were found to contain significantly more fat than the lean. At 10 d 20% more fat was present and by 17 d the increase was 72%. The obob mice at 28 d contained nearly three times as much fat as the lean. 3. Carcass energy was significantly higher in obob mice at all ages investigated. 4. Other changes in body composition found in the 28 d obob mice, i.e. a reduction in total carcass nitrogen and water content, were already established in the 17-d-old mice but differences at 10 and 12 d were not apparent. 5. The livers of obob mice were significantly heavier than those from lean control mice at 28 d but no differences were detected at the earlier ages. 6. The results are discussed with reference to the early origin of obesity in obob mice.

使用“冷应激”试验对10日龄、12日龄、17日龄和28日龄的obob和瘦型（ob+和++）小鼠的身体组成进行了研究，以区分这两组小鼠。2. 在这些年龄阶段的每个时间点，发现obob小鼠的脂肪含量均显著高于瘦型小鼠。在10日龄时，obob小鼠的脂肪含量多出20%，到17日龄时，这一增幅达到72%。28日龄的obob小鼠的脂肪含量几乎是瘦型小鼠的三倍。3. 在所有研究的年龄阶段，obob小鼠的胴体能量均显著更高。4. 在28日龄的obob小鼠中发现的身体组成的其他变化，即胴体总氮和水分含量的降低，在17日龄的小鼠中就已经出现，但在10日龄和12日龄时差异不明显。5. 28日龄时，obob小鼠的肝脏明显比瘦型对照小鼠的肝脏更重，但在较早年龄阶段未检测到差异。6. 参考obob小鼠肥胖的早期起源对结果进行了讨论。