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血清学分型在1970 - 1978年产气荚膜梭菌食物中毒暴发调查中的应用

Application of serological typing to the investigation of outbreaks of Clostridium perfringens food poisoning, 1970-1978.

作者信息

Stringer M F, Turnbull P C, Gilbert R J

出版信息

J Hyg (Lond). 1980 Jun;84(3):443-56. doi: 10.1017/s002217240002698x.

Abstract

Serological typing was used as an epidemiological tool in the investigation of 524 outbreaks of Clostridium perfringens food poisoning in the United Kingdom and 37 outbreaks in other countries. Five thousand five hundred and fifty-four (77%) of 7245 strains of C. perfringens associated with the 561 outbreaks were typable with the 75 Food Hygiene Laboratory antisera; in 354 (63%) of these outbreaks a specific serotype was established as being responsible for the outbreak. An assessment is made of the ability of two additional sets of antisera, prepared against 34 American and 34 Japanese strains of C. perfringens, to increase the number of strains which can be typed. The extent of cross-reaction between the three sets of antisera was determined and the results are discussed in relation to the source and history of the type strains.

摘要

血清学分型被用作一种流行病学工具,用于调查英国的524起产气荚膜梭菌食物中毒暴发事件以及其他国家的37起暴发事件。与这561起暴发事件相关的7245株产气荚膜梭菌中,有5554株(77%)可用75种食品卫生实验室抗血清进行分型;在其中354起(63%)暴发事件中,确定了一种特定血清型为暴发的病因。评估了另外两组针对34株美国产气荚膜梭菌菌株和34株日本产气荚膜梭菌菌株制备的抗血清增加可分型菌株数量的能力。确定了这三组抗血清之间的交叉反应程度,并结合分型菌株的来源和历史对结果进行了讨论。

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