Wells A, Koide N, Stein H, Gerdes J, Klein G
J Gen Virol. 1983 Feb;64 (Pt 2):449-53. doi: 10.1099/0022-1317-64-2-449.
Polyvalent serum directed against C3 receptors was employed in an attempt to block Epstein-Barr virus (EBV) binding to virus receptor-containing cell lines. The serum eliminated 90% of virus binding to Daudi and BJAB, lines which express only the C3d receptor. Raji and Ramos cells, which express the C3d, C3b and C3bi receptors, still adsorbed 70% of their virus capacity in the presence of excess antiserum. These effects were independent of the virus strain. In the light of previous reports, these data imply that, although the two receptors, EBV and C3d, are closely associated, the binding sites of EBV and complement are distinct. Additionally, an unusual EBV substrain-specific receptor found on U698 and P3HR-1/ASNP lines was shown to be independent of complement receptors.
使用针对C3受体的多价血清来试图阻断爱泼斯坦-巴尔病毒（EBV）与含病毒受体的细胞系的结合。该血清消除了90%的病毒与Daudi和BJAB细胞系的结合，这两种细胞系仅表达C3d受体。Raji和Ramos细胞表达C3d、C3b和C3bi受体，在存在过量抗血清的情况下，它们仍能吸附其病毒容量的70%。这些效应与病毒株无关。根据先前的报道，这些数据表明，尽管EBV和C3d这两种受体密切相关，但EBV和补体的结合位点是不同的。此外，在U698和P3HR-1/ASNP细胞系上发现的一种不寻常的EBV亚株特异性受体被证明与补体受体无关。
