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人类尿路结石的超微结构与发病机制

Ultrastructure and pathogenesis of human urinary calculi.

作者信息

Spector M, Garden N M, Rous S N

出版信息

Br J Urol. 1978 Feb;50(1):12-5. doi: 10.1111/j.1464-410x.1978.tb02757.x.

DOI:10.1111/j.1464-410x.1978.tb02757.x
PMID:630196
Abstract

The ultrastructure of human urinary calculi was studied using scanning and transmission electron microscopy. The hydroxyapatite constituent of the stones was often present in the form of sperical aggregates of the minute apatite crystallites (1 to 10 mu in diameter). In most cases, the sperical apatite deposits consisted of concentric lamellae of crystallites. The spherical apatite deposits, described in detail for the first time in urolithiasis, were similar to those found in a variety of calcified tissues including nephrocalcinosis and malakoplakia.

摘要

利用扫描电子显微镜和透射电子显微镜对人类尿路结石的超微结构进行了研究。结石中的羟基磷灰石成分通常以微小磷灰石微晶(直径1至10微米)的球形聚集体形式存在。在大多数情况下,球形磷灰石沉积物由微晶的同心薄片组成。这种在尿石症中首次详细描述的球形磷灰石沉积物,与在包括肾钙质沉着症和软斑病在内的多种钙化组织中发现的沉积物相似。

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Ultrastructure and pathogenesis of human urinary calculi.人类尿路结石的超微结构与发病机制
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引用本文的文献

1
What does the crystallography of stones tell us about their formation?结石的晶体结构能告诉我们它们是如何形成的?
Urolithiasis. 2017 Feb;45(1):11-18. doi: 10.1007/s00240-016-0951-0. Epub 2016 Nov 29.
2
Renal malakoplakia. Report of a case with giant Michaelis-Gutmann bodies.肾软斑症。1例伴有巨大迈克尔is-古特曼小体的病例报告。
Virchows Arch A Pathol Anat Histol. 1981;392(2):241-6. doi: 10.1007/BF00430824.
3
A multiple technique approach to the analysis of urinary calculi.一种用于分析尿路结石的多技术方法。
Urol Res. 1982;10(4):177-84. doi: 10.1007/BF00255941.
4
Electron microscopy of urinary calculi--some facts and artefacts.尿路结石的电子显微镜检查——一些事实与假象
Urol Res. 1984;12(1):17-22. doi: 10.1007/BF00256304.
5
Pancreatic calculi containing brushite: ultrastructure and pathogenesis.含透钙磷石的胰腺结石:超微结构与发病机制
Calcif Tissue Int. 1986 Nov;39(5):342-7. doi: 10.1007/BF02555202.