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中胚层混合瘤。通过中间丝蛋白分析进行诊断。

Mesodermal mixed tumor. Diagnosis by analysis of intermediate filament proteins.

作者信息

Ramaekers F C, Verheijen R H, Moesker O, Kant A, Vooijs G P, Herman C J

出版信息

Am J Surg Pathol. 1983 Jun;7(4):381-5.

PMID:6307070
Abstract

A 58-year-old patient presented with poorly differentiated adenocarcinoma, probably primary in the ovary and, later in the course of her illness, with pure pleomorphic rhabdomyosarcoma. There was no evidence by light or electron microscopy of a mixture of these two tumor types. Further analysis by immunoperoxidase demonstrated scattered desmin-positive (muscle) cells in the adenocarcinoma portion of the tumor, establishing the diagnosis of malignant mesodermal mixed tumor.

摘要

一名58岁患者被诊断为低分化腺癌,可能原发于卵巢,病程后期又出现了纯多形性横纹肌肉瘤。光学显微镜或电子显微镜检查均未发现这两种肿瘤类型混合存在的证据。通过免疫过氧化物酶进一步分析显示,肿瘤腺癌部分有散在的结蛋白阳性(肌肉)细胞,从而确诊为恶性中胚叶混合瘤。

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Mesodermal mixed tumor. Diagnosis by analysis of intermediate filament proteins.中胚层混合瘤。通过中间丝蛋白分析进行诊断。
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[A malignant mixed mesodermal tumor of the ovary].[卵巢恶性中胚叶混合瘤]
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引用本文的文献

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JSLS. 2019 Oct-Dec;23(4). doi: 10.4293/JSLS.2019.00038.
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Cytogenetic, morphologic and oncogene analysis of a cell line derived from a heterologous mixed mullerian tumor of the ovary.源自卵巢异源性混合苗勒管瘤的细胞系的细胞遗传学、形态学及癌基因分析。
In Vitro Cell Dev Biol Anim. 1997 May;33(5):325-31. doi: 10.1007/s11626-997-0001-x.
3
SV40 large T antigen-induced inhibition of terminal differentiation of primary skeletal muscle cells is associated with a block in the expression of MyoD and myogenin.
SV40大T抗原诱导的原代骨骼肌细胞终末分化抑制与MyoD和肌细胞生成素表达受阻有关。
Mol Biol Rep. 1994;20(3):143-8. doi: 10.1007/BF00990546.
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Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview.免疫组织化学鉴定人类肿瘤中中间丝蛋白抗体:综述
Histochem J. 1983 Jul;15(7):691-713. doi: 10.1007/BF01002988.
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Tissue-specific expression of a vimentin--desmin hybrid gene in transgenic mice.波形蛋白-结蛋白杂交基因在转基因小鼠中的组织特异性表达。
EMBO J. 1988 Apr;7(4):941-7. doi: 10.1002/j.1460-2075.1988.tb02899.x.
6
Malignant müllerian tumours of the uterus.子宫恶性苗勒管肿瘤
Arch Gynecol Obstet. 1988;241(4):209-19. doi: 10.1007/BF00931352.
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The use of antibodies to intermediate filament proteins in the differential diagnosis of lymphoma versus metastatic carcinoma.
Histochem J. 1985 Jan;17(1):57-70. doi: 10.1007/BF01003403.
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