Duncan J R, Hall C E, de Lisle C
Cornell Vet. 1978 Jan;68 Suppl 7:179-88.
Mycobacterium paratuberculosis infections and the disease states resulting in cattle are defined as spectral in nature. There is a spectrum of immunological response which complicates tests based on this. It is recommended that initial diagnosis of suspicious clinical cases be confirmed by direct fecal smears and a serological test such as immunodiffusion. Herd evaluation requires the application of fecal cultures plus immunodiffusion. Control requires rigid management hygiene measures, surveillance of the herd status and post mortem confirmation of salvaged animals.
副结核分枝杆菌感染以及牛群由此引发的疾病状态本质上被定义为具有谱系特征。存在一系列免疫反应，这使得基于此的检测变得复杂。建议通过直接粪便涂片和免疫扩散等血清学检测来确诊可疑临床病例。牛群评估需要进行粪便培养加免疫扩散检测。防控需要严格的管理卫生措施、对牛群状况的监测以及对扑杀动物的尸检确认。
