Kobayashi I, Murialdo H, Crasemann J M, Stahl M M, Stahl F W
Proc Natl Acad Sci U S A. 1982 Oct;79(19):5981-5. doi: 10.1073/pnas.79.19.5981.
Sequence chi, 5'G-C-T-G-G-T-G-G, locally enhances homologous recombination by recA and recBC proteins of Escherichia coli. Previous work showed that, in phage lambda, chi is more active in one orientation (leftward) than in the other (rightward). Inverting cos, the sequence for the mature DNA ends of lambda, reverses this orientation dependence: the rightward chi becomes fully active, and the leftward chi becomes relatively inactive. We surmise that chi action in phage lambda is coupled with DNA packaging or injection.
序列chi，5'G-C-T-G-G-T-G-G，局部增强了大肠杆菌recA和recBC蛋白介导的同源重组。先前的研究表明，在噬菌体λ中，chi在一个方向（向左）比在另一个方向（向右）更具活性。颠倒λ成熟DNA末端的序列cos，可逆转这种方向依赖性：向右的chi变得完全活跃，而向左的chi变得相对不活跃。我们推测噬菌体λ中chi的作用与DNA包装或注入相关。
