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[缺镁时高碘酸钠体外诱导小鼠脾淋巴细胞抑制活性的变化]

[Changes in the suppressive activity of splenic lymphocytes of mice induced in vitro by sodium periodate during magnesium deficiency].

作者信息

Claverie-Benureau S, Henrotte J G, Zinbi H, Agneray J, Gaudin-Harding F

出版信息

C R Seances Acad Sci III. 1983;296(21):985-8.

PMID:6311367
Abstract

Male DBA/2 Mice were kept on a magnesium deficient diet or a control diet. The antibody response of spleen cells, after in vitro immunization with Sheep red blood cells (SRBC) was determined comparatively in the two groups of Mice, from the 19th to the 22nd day of the diet. The effect of sodium periodate treatment on the induction of in vitro antibody suppressor cells was also studies. This treatment activated suppressor cells towards anti-SRBC response in the control group, but not in the Mg-deficient group (P less than 0.002). A greater sensitivity of periodate induced T suppressor cells to Mg deficiency is suggested by the present results.

摘要

雄性DBA/2小鼠被喂食缺镁饮食或对照饮食。在饮食的第19天至第22天,比较测定了两组小鼠经绵羊红细胞(SRBC)体外免疫后脾细胞的抗体反应。还研究了高碘酸钠处理对体外抗体抑制细胞诱导的影响。该处理激活了对照组中针对抗SRBC反应的抑制细胞,但在缺镁组中未激活(P小于0.002)。本研究结果提示高碘酸钠诱导的T抑制细胞对镁缺乏更为敏感。

相似文献

1
[Changes in the suppressive activity of splenic lymphocytes of mice induced in vitro by sodium periodate during magnesium deficiency].[缺镁时高碘酸钠体外诱导小鼠脾淋巴细胞抑制活性的变化]
C R Seances Acad Sci III. 1983;296(21):985-8.
2
[Suppressor effect induced by sodium periodate on the antibody response of mouse splenic cells in vitro : inhibition of this effect by sodium borohydride].[高碘酸钠对小鼠脾细胞体外抗体应答的抑制作用:硼氢化钠对该作用的抑制]
C R Seances Acad Sci D. 1979 Jun 11;288(21):1631-3.
3
Behavior of aldehyde moieties involved in the activation of suppressor cells by sodium periodate.高碘酸钠激活抑制细胞过程中醛基的作用。
J Immunol. 1987 Feb 15;138(4):1157-63.
4
[Production of suppressor factor(s) in the in vitro antibody response by periodate oxidized spleen cells].
C R Seances Acad Sci III. 1982 Nov 22;295(10):607-10.
5
Effect of magnesium deficiency and food restriction on the immune response in young mice.镁缺乏和食物限制对幼鼠免疫反应的影响。
Int J Vitam Nutr Res. 1978;48(3):290-5.
6
In vitro generation of splenic suppressor cells by trypsin.通过胰蛋白酶在体外生成脾脏抑制细胞。
Immunology. 1982 Jun;46(2):369-80.
7
Induction of suppressor cells by sodium periodate: the opposite expression of periodate-induced lymphocyte activation in spleen cells of normal and nude mice.高碘酸钠诱导抑制性细胞:正常小鼠和裸鼠脾细胞中高碘酸钠诱导的淋巴细胞活化的相反表达
Immunology. 1979 May;37(1):53-9.
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[Effect of rubomycin and carminomycin on suppressor cells participating in the regulation of the immune response].[柔红霉素和洋红霉素对参与免疫反应调节的抑制细胞的作用]
Antibiotiki. 1983 Apr;28(4):307-11.
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[Effect of suppressor cells on the formation of immunologic memory in mice of various strains].[抑制细胞对不同品系小鼠免疫记忆形成的影响]
Biull Eksp Biol Med. 1981 Dec;92(12):701-2.
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Effect of hypomagnesemia on allogeneic activation in mice.低镁血症对小鼠同种异体激活的影响。
Transpl Immunol. 2008 Nov;20(1-2):83-7. doi: 10.1016/j.trim.2008.07.005. Epub 2008 Aug 14.