Summers R J, Kuhar M J
Eur J Pharmacol. 1983 Jul 22;91(2-3):305-10. doi: 10.1016/0014-2999(83)90484-3.
The beta-adrenoceptor antagonist radioligand [125I]cyanopindolol (CYP) has been used to localize beta-adrenoceptors in rat kidney sections. [125I]CYP bound with high affinity to sites in rat kidney sections having the recognition characteristics of beta-adrenoceptors. Autoradiographic studies combined with histochemical techniques demonstrated that the beta-adrenoceptors were primarily located on renal glomeruli, distal and cortical collecting tubules rather than on proximal tubules or vascular elements.
β-肾上腺素能受体拮抗剂放射性配体[125I]氰吲哚洛尔（CYP）已被用于在大鼠肾脏切片中定位β-肾上腺素能受体。[125I]CYP与大鼠肾脏切片中具有β-肾上腺素能受体识别特征的位点高亲和力结合。放射自显影研究结合组织化学技术表明，β-肾上腺素能受体主要位于肾小球、远曲小管和皮质集合管，而非近端小管或血管成分上。
