Effect of dimethyl sulfate on the secondary structure of DNA.
作者信息
Wani A A, Hadi S M, Ahmad N S
出版信息
Experientia. 1978 Mar 15;34(3):392-4. doi: 10.1007/BF01923056.
PMID:631278
Abstract
Hydroxyapatite chromatography has been used to demonstrate that alkylation of DNA at neutral pH may lead to denaturation under conditions where no significant depurination occurs. Presence of salt has a preventive effect on such denaturation.
摘要
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