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Effect of dimethyl sulfate on the secondary structure of DNA.

作者信息

Wani A A, Hadi S M, Ahmad N S

出版信息

Experientia. 1978 Mar 15;34(3):392-4. doi: 10.1007/BF01923056.

DOI:10.1007/BF01923056
PMID:631278
Abstract

Hydroxyapatite chromatography has been used to demonstrate that alkylation of DNA at neutral pH may lead to denaturation under conditions where no significant depurination occurs. Presence of salt has a preventive effect on such denaturation.

摘要

相似文献

1
Effect of dimethyl sulfate on the secondary structure of DNA.
Experientia. 1978 Mar 15;34(3):392-4. doi: 10.1007/BF01923056.
2
Effect of alkylation on the secondary structure of DNA.
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3
Studies on the cytotoxicity of Myleran and dimethyl Myleran.马利兰和二甲马利兰的细胞毒性研究。
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J Mol Biol. 2001 Feb 16;306(2):169-88. doi: 10.1006/jmbi.2000.4371.
5
Chromatography of nucleic acids on hydroxyapatite. I. Chromatography of native DNA.核酸在羟基磷灰石上的色谱分析。I. 天然DNA的色谱分析。
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Fluoride ion catalyzed alkylation of nucleic acid derivatives using trialkyl phosphates, dialkyl sulfates and alkyl methanesulfonates.氟离子催化的使用磷酸三烷基酯、硫酸二烷基酯和甲磺酸烷基酯的核酸衍生物的烷基化反应。
Nucleic Acids Res. 1979;6(6):2261-73. doi: 10.1093/nar/6.6.2261.
7
A phase diagram of the binding of mismatched duplex DNAs to hydroxyapatite.
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Chromatography of nucleic acids on hydroxyapatite. II. Chromatography of denatured DNA.核酸在羟基磷灰石上的色谱分析。II. 变性DNA的色谱分析。
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10
Hydroxyapatite fractionation procedures in the study of the mammalian genome.哺乳动物基因组研究中的羟基磷灰石分级分离程序。
Biochem J. 1967 Oct;105(1):163-9. doi: 10.1042/bj1050163.

本文引用的文献

1
Physicochemical changes produced in DNA after alkylation.烷基化后DNA产生的物理化学变化。
Arch Biochem Biophys. 1962 Apr;97:80-93. doi: 10.1016/0003-9861(62)90047-4.
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FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES.核酸及其组成核苷酸烷基化的进一步研究
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Distribution density of nucleotides within a desoxyribonucleic acid chain.脱氧核糖核酸链内核苷酸的分布密度。
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Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation.N-甲基-N'-硝基-N-亚硝基胍对培养的哺乳动物细胞中脱氧核糖核酸的甲基化作用。细胞内硫醇浓度对甲基化程度的影响以及鸟嘌呤的6-氧原子作为甲基化位点的情况。
Biochem J. 1970 Feb;116(4):693-707. doi: 10.1042/bj1160693.
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Nuclease for DNA apurinic sites may be involved in the maintenance of DNA in normal cells.用于DNA脱嘌呤位点的核酸酶可能参与正常细胞中DNA的维持。
Nat New Biol. 1973 Jul 18;244(133):67-9. doi: 10.1038/newbio244067a0.
6
Alkylation of phosphates and stability of phosphate triesters in DNA.DNA 中磷酸酯的烷基化及磷酸三酯的稳定性
Eur J Biochem. 1972 Nov 21;31(1):103-11. doi: 10.1111/j.1432-1033.1972.tb02506.x.
7
Nuclease for DNA apurinic sites in chicken liver.鸡肝中DNA脱嘌呤位点的核酸酶
Experientia. 1977 Apr 15;33(4):418-20. doi: 10.1007/BF01922186.
8
Effects of alkylation by dimethyl sulfate, nitrogen mustard, and mitomycin C on DNA structure as studied by the ethidium binding assay.
Can J Biochem. 1976 Dec;54(12):1047-54. doi: 10.1139/o76-153.