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鸡肝中DNA脱嘌呤位点的核酸酶

Nuclease for DNA apurinic sites in chicken liver.

作者信息

Rizvi R Y, Hadi S M

出版信息

Experientia. 1977 Apr 15;33(4):418-20. doi: 10.1007/BF01922186.

DOI:10.1007/BF01922186
PMID:862720
Abstract

Chicken liver crude extract produced acid-soluble diphenylamine-positive material in the presence of depurinated and alkylated DNA, while the formation of such material from normal and single stranded DNA was comparatively low. The maximum acid-soluble material produced was not increased further by alkali, indicating that the enzymatic action is mostly directed towards apurinic sites.

摘要

鸡肝粗提取物在存在脱嘌呤和烷基化DNA的情况下产生酸溶性二苯胺阳性物质，而由正常DNA和单链DNA形成此类物质的量相对较低。所产生的最大酸溶性物质不会因碱而进一步增加，这表明酶促作用主要针对无嘌呤位点。

相似文献

1
Nuclease for DNA apurinic sites in chicken liver.鸡肝中DNA脱嘌呤位点的核酸酶
Experientia. 1977 Apr 15;33(4):418-20. doi: 10.1007/BF01922186.
2
Purification and properties of a Bacillus subtilis endonuclease specific for apurinic sites in DNA.枯草芽孢杆菌DNA脱嘌呤位点特异性内切核酸酶的纯化及性质
J Biol Chem. 1978 Dec 10;253(23):8559-63.
3
A barley endonuclease specific for apurinic DNA. Isolation and partial characterization.一种对脱嘌呤DNA具有特异性的大麦内切核酸酶。分离及部分特性鉴定。
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4
Purification of Escherichia coli endonuclease specific for apurinic sites in DNA.对DNA中脱嘌呤位点具有特异性的大肠杆菌内切核酸酶的纯化
J Biol Chem. 1975 Oct 25;250(20):8214-9.
5
DNA binding activity from cultured human fibrolasts that is specific for partially depurinated DNA and that inserts purines into apurinic sites.来自培养的人成纤维细胞的DNA结合活性，该活性对部分脱嘌呤的DNA具有特异性，并能将嘌呤插入无嘌呤位点。
Proc Natl Acad Sci U S A. 1979 Jan;76(1):141-4. doi: 10.1073/pnas.76.1.141.
6
Apurinic acid endonuclease activity from mouse epidermal cells.来自小鼠表皮细胞的脱嘌呤酸内切酶活性。
Nucleic Acids Res. 1979 Jun 25;6(8):2901-17. doi: 10.1093/nar/6.8.2901.
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Deoxyribonuclease IV from rat liver chromatin and the excision of apurinic sites from depurinated DNA.来自大鼠肝脏染色质的脱氧核糖核酸酶IV与脱嘌呤DNA中无嘌呤位点的切除
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Relation between Escherichia coli endonucleases specific for apurinic sites in DNA and exonuclease III.DNA中对脱嘌呤位点具有特异性的大肠杆菌核酸内切酶与核酸外切酶III之间的关系。
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9
A single apurinic site can elicit BAL 31 nuclease-catalyzed cleavage in duplex DNA.
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10
Apurinic/apyrimidinic endonucleases in repair of pyrimidine dimers and other lesions in DNA.脱嘌呤/脱嘧啶内切核酸酶在DNA嘧啶二聚体及其他损伤修复中的作用
Proc Natl Acad Sci U S A. 1980 Aug;77(8):4602-6. doi: 10.1073/pnas.77.8.4602.

引用本文的文献

1
Effect of dimethyl sulfate on the secondary structure of DNA.
Experientia. 1978 Mar 15;34(3):392-4. doi: 10.1007/BF01923056.

本文引用的文献

1
Distribution density of nucleotides within a desoxyribonucleic acid chain.脱氧核糖核酸链内核苷酸的分布密度。
J Biol Chem. 1953 Aug;203(2):673-88.
2
The intermediate in the degradation of DNA alkylated with a monofunctional alkylating agent.被单功能烷基化剂烷基化的DNA降解过程中的中间体。
Biochim Biophys Acta. 1970 Jul 16;213(1):14-25. doi: 10.1016/0005-2787(70)90003-1.
3
Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid.大肠杆菌核酸内切酶II。II。酶的性质以及对烷基化和天然脱氧核糖核酸降解的研究。
J Biol Chem. 1969 Nov 10;244(21):5879-89.
4
Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid.大肠杆菌的核酸内切酶II。部分脱嘌呤脱氧核糖核酸的降解
Biochemistry. 1971 Dec 21;10(26):4986-93. doi: 10.1021/bi00802a024.
5
In vitro repair of apurinic sites in DNA.DNA中脱嘌呤位点的体外修复
Proc Natl Acad Sci U S A. 1974 Jun;71(6):2273-5. doi: 10.1073/pnas.71.6.2273.
6
The enzymatic release of O6-methylguanine and 3-methyladenine from DNA reacted with the carcinogen N-methyl-N-nitrosourea.与致癌物N-甲基-N-亚硝基脲反应的DNA中O6-甲基鸟嘌呤和3-甲基腺嘌呤的酶促释放。
Proc Natl Acad Sci U S A. 1974 May;71(5):2022-6. doi: 10.1073/pnas.71.5.2022.
7
An endonuclease for depurinated DNA in rat liver.大鼠肝脏中一种作用于脱嘌呤DNA的核酸内切酶。
Can J Biochem. 1973 Jul;51(7):1003-9. doi: 10.1139/o73-130.
8
Nuclease for DNA apurinic sites may be involved in the maintenance of DNA in normal cells.用于DNA脱嘌呤位点的核酸酶可能参与正常细胞中DNA的维持。
Nat New Biol. 1973 Jul 18;244(133):67-9. doi: 10.1038/newbio244067a0.
9
Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid.双链脱氧核糖核酸中脱嘌呤位点的链断裂速率。
Biochemistry. 1972 Sep 12;11(19):3618-23. doi: 10.1021/bi00769a019.
10
An endonuclease for depurinated DNA in Escherichia coli B.大肠杆菌B中用于脱嘌呤DNA的核酸内切酶。
Can J Biochem. 1972 Feb;50(2):217-24. doi: 10.1139/o72-029.