Copeland T D, Oroszlan S, Kalyanaraman V S, Sarngadharan M G, Gallo R C
FEBS Lett. 1983 Oct 17;162(2):390-5. doi: 10.1016/0014-5793(83)80793-5.
The complete amino acid sequence of human T-cell leukemia virus (HTLV) structural protein p15 has been determined. The intact protein and peptides generated by enzymatic digestion and acid cleavage were purified by reversed-phase liquid chromatography and subjected to semi-automated Edman degradation. HTLV p15 is a basic linear polypeptide composed of 85 amino acids with Mr 9458. The primary structure indicates that HTLV p15 is homologous to the nucleic acid binding proteins of other type-C retroviruses and especially related to bovine leukemia virus p12.
