Rodrigues K, Sumpter J P
Gen Comp Endocrinol. 1983 Sep;51(3):454-9. doi: 10.1016/0016-6480(83)90062-x.
Acid extracts of neurointermediate lobe (NIL) and pars distalis (PD) of the pituitary gland of the rainbow trout were radioimmunoassayed for alpha-melanocyte-stimulating hormone (alpha-MSH), beta-melanocyte-stimulating hormone (beta-MSH), adrenocorticotrophin (ACTH), and endorphin. The majority of the alpha-MSH, beta-MSH, and endorphin was present in the NIL; the small amount of these peptides present in the PD may be native to this lobe, or may be due to slight contamination with NIL material--it is not possible to distinguish between these possibilities at present. All the ACTH was present in the PD. These results support the hypothesis that throughout the vertebrates proopiomelanocortin is cleaved to smaller peptides in the NIL than it is in the PD.
用放射免疫分析法测定虹鳟垂体神经中间叶（NIL）和远侧部（PD）的酸性提取物中的α-黑素细胞刺激素（α-MSH）、β-黑素细胞刺激素（β-MSH）、促肾上腺皮质激素（ACTH）和内啡肽。大部分α-MSH、β-MSH和内啡肽存在于神经中间叶；远侧部中存在的少量这些肽可能是该叶所固有的，也可能是由于轻微污染了神经中间叶的物质——目前无法区分这两种可能性。所有促肾上腺皮质激素都存在于远侧部。这些结果支持了这样的假说，即整个脊椎动物中，阿黑皮素原在神经中间叶比在远侧部被切割成更小的肽。
