前列腺素在体内和体外均无法提高小鼠表皮中的环磷酸腺苷水平。
Prostaglandins fail to elevate cyclic AMP levels in mouse epidermis in vivo and in vitro.
作者信息
Garte S J, Belman S
出版信息
J Invest Dermatol. 1983 Nov;81(5):422-3. doi: 10.1111/1523-1747.ep12522583.
PMID:6313812
Abstract
Prostaglandin E1 had no effect on mouse epidermal cyclic AMP levels either when applied percutaneously to shaven skin or when incubated in vitro with epidermal homogenates. Neither prostaglandin E1 nor E2 had any effect on cyclic AMP levels in a line of cultured mouse epidermal cells at doses from 0.1-10 microM.
摘要
前列腺素E1无论是经皮应用于剃毛后的皮肤，还是在体外与表皮匀浆孵育，均对小鼠表皮环磷酸腺苷（cAMP）水平无影响。前列腺素E1和E2在0.1 - 10微摩尔的剂量下，对一系列培养的小鼠表皮细胞中的环磷酸腺苷水平均无任何影响。
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