Doran J E
Vox Sang. 1983;45(5):337-48. doi: 10.1111/j.1423-0410.1983.tb01925.x.
Within recent years, the physiological roles of fibronectin (Fn) have begun to be elucidated. This review examines Fn's opsonic capabilities with respect to bacteria and microparticulates. Fn's ability to promote the phagocytosis of these targets by monocytes, macrophages, and neutrophils is discussed in detail, as are the possible mechanisms through which Fn mediates these interactions. The controversies concerning the physiological importance of Fn for host homeostasis and its use as an indicator of reticuloendothelial system function are also addressed in this review.
近年来，纤连蛋白（Fn）的生理作用已开始得到阐明。本综述考察了Fn对细菌和微粒的调理吞噬能力。详细讨论了Fn促进单核细胞、巨噬细胞和中性粒细胞对这些靶标的吞噬作用的能力，以及Fn介导这些相互作用的可能机制。本综述还探讨了有关Fn对宿主稳态的生理重要性及其作为网状内皮系统功能指标的争议。
