肠道中天然胶原蛋白的消化。
Digestion of native collagen in the gut.
作者信息
Harkness M L, Harkness R D, Venn M F
出版信息
Gut. 1978 Mar;19(3):240-3. doi: 10.1136/gut.19.3.240.
Abstract
The digestion and absorption of collagen, native and artificially cross-linked, has been examined in the rat and the Gaboon viper, by feeding known quantities and measuring the hydroxy-proline content of the faeces and of the contents of the gut at different levels, and comparing with an unabsorbable marker (polyethylene glycol). Incubation of collagen in vitro with pepsin at 37 degrees C at pH 1.5 followed by trypsin or chymotrypsin converted about 40% into dialysable material.
摘要
通过给大鼠和加蓬咝蝰喂食已知量的天然和人工交联胶原蛋白，并测量不同肠段粪便和肠内容物中的羟脯氨酸含量，同时与不可吸收标记物（聚乙二醇）进行比较，研究了胶原蛋白的消化和吸收情况。在体外，将胶原蛋白于37摄氏度、pH值为1.5的条件下与胃蛋白酶一起孵育，随后再与胰蛋白酶或糜蛋白酶一起孵育，结果约40%的胶原蛋白转化为可透析物质。
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