Bicker U
Fortschr Med. 1978 Mar 30;96(12):661-4.
A new class of compounds, the 2-cyanaziridines, has immune-modulating properties. This immune-modulation was proved by the influence on the delayed type hypersensitivity reaction, the increase of the lymphocyte transformation by T-cell-specific mitogens ConA and PHA, the increase of phagocytosis of macrophages, the increase of resistance against bacterial, fungal and virus infections and by the influence on various transplantation tumors in mice and rats.
一类新型化合物,即2-氰基氮丙啶,具有免疫调节特性。这种免疫调节作用通过以下方面得到证实:对迟发型超敏反应的影响、T细胞特异性丝裂原刀豆蛋白A(ConA)和植物血凝素(PHA)导致的淋巴细胞转化增加、巨噬细胞吞噬作用增强、对细菌、真菌和病毒感染抵抗力的提高以及对小鼠和大鼠各种移植肿瘤的影响。