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异丙肾上腺素刺激C6细胞中的脂质甲基化，而不影响膜流动性。

Isoproterenol stimulates lipid methylation in C6 cells without affecting membrane fluidity.

作者信息

McKenzie R C, Brophy P J

出版信息

FEBS Lett. 1983 Dec 12;164(2):244-6. doi: 10.1016/0014-5793(83)80294-4.

DOI:10.1016/0014-5793(83)80294-4
PMID:6317449
Abstract

C6 glioma cells were stimulated with the beta-adrenergic agonist isoproterenol. The rate of cyclic AMP accumulation and lipid methylation increased. However, the elevated rate of lipid methylation did not affect the fluidity of the plasma membrane. It is concluded that lipid methylation is not responsible for making the plasma membrane more fluid during the beta-adrenergic response.

摘要

用β-肾上腺素能激动剂异丙肾上腺素刺激C6胶质瘤细胞。环磷酸腺苷积累速率和脂质甲基化增加。然而，脂质甲基化速率的升高并未影响质膜的流动性。得出的结论是，在β-肾上腺素能反应过程中，脂质甲基化与使质膜更具流动性无关。

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1
Isoproterenol stimulates lipid methylation in C6 cells without affecting membrane fluidity.异丙肾上腺素刺激C6细胞中的脂质甲基化，而不影响膜流动性。
FEBS Lett. 1983 Dec 12;164(2):244-6. doi: 10.1016/0014-5793(83)80294-4.
2
Desensitization of catecholamine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells. Role of cyclic AMP and protein synthesis.大鼠胶质瘤C6细胞中儿茶酚胺刺激的腺苷酸环化酶脱敏及β-肾上腺素能受体下调。环磷酸腺苷和蛋白质合成的作用。
Mol Pharmacol. 1984 Sep;26(2):206-13.
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Effect of lindane upon the beta-adrenergic stimulation of cyclic AMP accumulation in rat renal cortical tubules caused by alterations in membrane fluidity.
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Induction of refractoriness to isoproterenol by prior treatment of C6-2B rat astrocytoma cells with cholera toxin.用霍乱毒素预先处理C6-2B大鼠星形细胞瘤细胞可诱导其对异丙肾上腺素产生耐受性。
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beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling.β-肾上腺素能受体激动剂可增加磷脂甲基化、膜流动性以及β-肾上腺素能受体与腺苷酸环化酶的偶联。
Proc Natl Acad Sci U S A. 1979 Jan;76(1):368-72. doi: 10.1073/pnas.76.1.368.
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Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells.
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Differences in the beta-adrenergic responsiveness between high and low passage rat glioma C6 cells.
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Effect of adrenergic agents on alpha-amylase release and adenosine 3',5'-monophosphate accumulation in rat parotid tissue slices.肾上腺素能药物对大鼠腮腺组织切片中α-淀粉酶释放及3',5'-环磷酸腺苷积累的影响。
Biochim Biophys Acta. 1975 May 5;392(1):82-94. doi: 10.1016/0304-4165(75)90168-3.
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Role of lindane in membranes. Effects on membrane fluidity and activity of membrane-bound proteins.林丹在膜中的作用。对膜流动性和膜结合蛋白活性的影响。
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Functional endothelin-1 receptors in rat astrocytoma C6.大鼠星形细胞瘤C6中的功能性内皮素-1受体
Eur J Pharmacol. 1991 Mar 25;206(3):191-8. doi: 10.1016/s0922-4106(05)80018-5.

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Bridging the gap between protein carboxyl methylation and phospholipid methylation to understand glucose-stimulated insulin secretion from the pancreatic beta cell.弥合蛋白质羧基甲基化与磷脂甲基化之间的差距，以了解胰腺β细胞的葡萄糖刺激胰岛素分泌。
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The effect of polar head group substitution on phospholipid methylation and the beta-adrenergic response in C6 glial cells.极性头部基团取代对C6神经胶质细胞中磷脂甲基化及β-肾上腺素能反应的影响。
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