Cappelli J, Morobe J, Van Laethem A, Musin L
Acta Chir Belg. 1983 Nov-Dec;83(6):440-3.
The object of this study was to value the efficacy of reflux oesophagitis treatment by H2-blockers. Fifty-one patients were treated by Cimetidine or Ranitidine. After three months, we note a clinical improvement in 84% of cases and a regression of the endoscopic lesions in 61% of cases. A long term overlooking shows a high number of recurrences when the treatment is stopped, whereas the chronic treatment has essentially a stabilizing effect on the lesions.
本研究的目的是评估H2受体阻滞剂治疗反流性食管炎的疗效。51例患者接受了西咪替丁或雷尼替丁治疗。三个月后，我们注意到84%的病例有临床改善，61%的病例内镜下病变有所消退。长期观察显示，治疗停止后复发率很高，而长期治疗对病变基本上有稳定作用。
