Lindgärde F, Larsson L
Hum Nutr Clin Nutr. 1984 Jan;38(1):39-45.
The effect of adding a purified form of wheat fibre (10.5 g/d) to a lipid-lowering diet was investigated in a placebo-controlled, double-blind, cross-over study (two 8-week periods) in 12 males (36-46 years old) with hypercholesterolaemia. Normolipidaemic men (n = 14, 45-46 years old) were used as controls in evaluation of the seasonal variation of serum lipids and lipoproteins in untreated subjects. Addition of wheat fibre was associated with non-significant decreases in cholesterol in very low and low density lipoproteins and a significant increase in cholesterol in high density lipoprotein. Serum cholesterol was unchanged in the treatment group but increased in the untreated control group. It is concluded that enrichment of a lipid-lowering diet with concentrated wheat fibre may be of value in the treatment of hypercholesterolaemia.
在一项安慰剂对照、双盲、交叉研究（两个8周周期）中，对12名患有高胆固醇血症的男性（36 - 46岁）进行了研究，观察在降脂饮食中添加纯化形式的小麦纤维（10.5克/天）的效果。在评估未治疗受试者血清脂质和脂蛋白的季节性变化时，以血脂正常的男性（n = 14，45 - 46岁）作为对照。添加小麦纤维与极低密度脂蛋白和低密度脂蛋白中的胆固醇非显著降低以及高密度脂蛋白中的胆固醇显著增加有关。治疗组的血清胆固醇没有变化，但未治疗的对照组血清胆固醇有所增加。得出的结论是，在降脂饮食中添加浓缩小麦纤维可能对高胆固醇血症的治疗有价值。
