弯曲热单孢菌的一种抗分解代谢物阻遏突变体中的纤维素酶生物合成
Cellulase biosynthesis in a catabolite repression-resistant mutant of Thermomonospora curvata.
作者信息
Fennington G, Neubauer D, Stutzenberger F
出版信息
Appl Environ Microbiol. 1984 Jan;47(1):201-4. doi: 10.1128/aem.47.1.201-204.1984.
Abstract
A catabolite repression-resistant mutant of the thermophilic actinomycete Thermomonospora curvata was obtained by treatment with ethyl methanesulfonate and UV light. Cellulase biosynthesis was undiminished by glucose, 2-deoxyglucose, or alpha-methyl glucoside, which are potent repressors in the wild type. Intracellular cyclic AMP levels were higher in the mutant in both the absence and the presence of repressors.
摘要
通过甲磺酸乙酯和紫外线处理，获得了嗜热放线菌弯曲热单孢菌的一种抗分解代谢物阻遏突变体。在野生型中作为强效阻遏物的葡萄糖、2-脱氧葡萄糖或α-甲基葡萄糖苷，对该突变体的纤维素酶生物合成没有抑制作用。在不存在和存在阻遏物的情况下，该突变体细胞内的环磷酸腺苷水平均较高。
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