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弯曲嗜热单孢菌模式菌株(B9)的全基因组序列

Complete genome sequence of Thermomonospora curvata type strain (B9).

作者信息

Chertkov Olga, Sikorski Johannes, Nolan Matt, Lapidus Alla, Lucas Susan, Del Rio Tijana Glavina, Tice Hope, Cheng Jan-Fang, Goodwin Lynne, Pitluck Sam, Liolios Konstantinos, Ivanova Natalia, Mavromatis Konstantinos, Mikhailova Natalia, Ovchinnikova Galina, Pati Amrita, Chen Amy, Palaniappan Krishna, Djao Olivier D Ngatchou, Land Miriam, Hauser Loren, Chang Yun-Juan, Jeffries Cynthia D, Brettin Thomas, Han Cliff, Detter John C, Rohde Manfred, Göker Markus, Woyke Tanja, Bristow James, Eisen Jonathan A, Markowitz Victor, Hugenholtz Philip, Klenk Hans-Peter, Kyrpides Nikos C

出版信息

Stand Genomic Sci. 2011 Feb 20;4(1):13-22. doi: 10.4056/sigs.1453580.

Abstract

Thermomonospora curvata Henssen 1957 is the type species of the genus Thermomonospora. This genus is of interest because members of this clade are sources of new antibiotics, enzymes, and products with pharmacological activity. In addition, members of this genus participate in the active degradation of cellulose. This is the first complete genome sequence of a member of the family Thermomonosporaceae. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 5,639,016 bp long genome with its 4,985 protein-coding and 76 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

摘要

弯曲嗜热单孢菌(Thermomonospora curvata)亨森于1957年命名,是嗜热单孢菌属的模式种。该属备受关注,因为这一进化枝的成员是新抗生素、酶以及具有药理活性的产物的来源。此外,该属成员参与纤维素的活性降解。这是嗜热单孢菌科成员的首个完整基因组序列。在此,我们描述该生物体的特征,以及完整的基因组序列和注释。这个长度为5,639,016 bp的基因组,含有4,985个蛋白质编码基因和76个RNA基因,是细菌和古菌基因组百科全书项目的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6f2/3072092/4c01c77cccc8/sigs.1453580-f1.jpg

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