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多氯联苯(PCBs)和多溴联苯(PBBs)通过人类胎盘并进入母乳的转移情况。

The transfer of polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs) across the human placenta and into maternal milk.

作者信息

Jacobson J L, Fein G G, Jacobson S W, Schwartz P M, Dowler J K

出版信息

Am J Public Health. 1984 Apr;74(4):378-9. doi: 10.2105/ajph.74.4.378.

Abstract

Cord serum and maternal milk levels of polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs) were examined in relation to maternal serum levels. Maternal serum levels were significantly higher than cord serum levels for both types of compounds. Placental passage was indicated by significant maternal to cord serum correlations for both PCBs (r = .42) and PBBs (r = .81). Correlations between maternal serum and milk levels were similar. Higher PBB correlations were probably due to greater reliability in the measurement of PBB levels in serum and milk.

摘要

检测了脐带血清和母乳中多氯联苯(PCBs)及多溴联苯(PBBs)的水平,并与母体血清水平进行关联分析。两种化合物的母体血清水平均显著高于脐带血清水平。PCB(r = 0.42)和PBB(r = 0.81)的母体血清与脐带血清之间均存在显著相关性,表明有胎盘转运。母体血清与母乳水平之间的相关性相似。PBB相关性较高可能是由于血清和母乳中PBB水平测量的可靠性更高。

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