Spanò C, Fazzolari Nesci A, Pecoraro G, Perino A, Gullotti A, Patti S, Mazara M
Boll Soc Ital Biol Sper. 1983 Dec 30;59(12):1896-902.
The TORCH group: toxoplasma, rubeola, cytomegalovirus (CMV), herpes virus hominis (HSV) and also the B-virus of hepatitis (HBV) determine congenital malformations in the newborns. For this reason, the Authors leaded an epidemiologic study testing with some antibodies (anti-TORCH and anti-HBV) the serum of groups of mother-newborn of the Obstetrical Clinic of Palermo. This study became manageable because now there are available high specific immunoenzymatic methods, for example ELISA, the passive haemoagglutination and the haemoagglutination-inhibition. In our people, high concentration of rubeola, HSV and CMV and very low concentration of toxoplasma and HBV are shown. The frequency of malformation is related with the subclinical infection. The Authors suggest to extend same investigation at an higher number of pregnant women to prevent these congenital malformations.
TORCH组：弓形虫、风疹病毒、巨细胞病毒（CMV）、人疱疹病毒（HSV）以及乙型肝炎病毒（HBV）可导致新生儿先天性畸形。因此，作者开展了一项流行病学研究，用一些抗体（抗TORCH和抗HBV）检测巴勒莫产科诊所母婴群体的血清。由于现在有了高特异性免疫酶法，如酶联免疫吸附测定（ELISA）、被动血凝试验和血凝抑制试验，这项研究变得可行。在我们的研究对象中，显示出风疹病毒、HSV和CMV浓度高，而弓形虫和HBV浓度极低。畸形的发生率与亚临床感染有关。作者建议对更多孕妇进行同样的调查，以预防这些先天性畸形。
