蜂毒明肽，一种对一类钙依赖性钾通道具有特异性的神经毒素。 - Suppr

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超能文献

Apamin, a neurotoxin specific for one class of Ca2+-dependent K+ channels.

作者信息

Lazdunski M

出版信息

Cell Calcium. 1983 Dec;4(5-6):421-8. doi: 10.1016/0143-4160(83)90018-0.

DOI:10.1016/0143-4160(83)90018-0

PMID:6323004

Abstract

摘要

相似文献

Apamin, a neurotoxin specific for one class of Ca2+-dependent K+ channels.蜂毒明肽，一种对一类钙依赖性钾通道具有特异性的神经毒素。

Cell Calcium. 1983 Dec;4(5-6):421-8. doi: 10.1016/0143-4160(83)90018-0.

Apamin: a specific toxin to study a class of Ca2+-dependent K+ channels.蜂毒明肽：一种用于研究一类钙依赖性钾通道的特异性毒素。

J Physiol (Paris). 1984;79(4):259-64.

Identification of a protein component of the Ca2+-dependent K+ channel by affinity labelling with apamin.

Biochem Biophys Res Commun. 1982 Aug 31;107(4):1577-82. doi: 10.1016/s0006-291x(82)80180-0.

Apamin as a selective blocker of the calcium-dependent potassium channel in neuroblastoma cells: voltage-clamp and biochemical characterization of the toxin receptor.蜂毒明肽作为神经母细胞瘤细胞中钙依赖性钾通道的选择性阻滞剂：毒素受体的电压钳制和生化特性

Proc Natl Acad Sci U S A. 1982 Feb;79(4):1308-12. doi: 10.1073/pnas.79.4.1308.

Effects of apamin on the outward potassium current of isolated frog skeletal muscle fibres.蜂毒明肽对离体青蛙骨骼肌纤维外向钾电流的影响。

Pflugers Arch. 1984 Oct;402(2):222-4. doi: 10.1007/BF00583339.

Differential effects of apamin on Ca2+-dependent K+ currents in bullfrog sympathetic ganglion cells.蜂毒明肽对牛蛙交感神经节细胞中钙依赖性钾电流的不同作用。

Neurosci Lett. 1986 Sep 12;69(3):233-8. doi: 10.1016/0304-3940(86)90485-4.

[Effect of the neurotoxin apamin on ion currents in membranes of heart fibers].

Biofizika. 1988 Jan-Feb;33(1):109-12.

The all-or-none role of innervation in expression of apamin receptor and of apamin-sensitive Ca2+-activated K+ channel in mammalian skeletal muscle.神经支配在哺乳动物骨骼肌中蜂毒明肽受体及蜂毒明肽敏感的钙激活钾通道表达中的全或无作用。

Proc Natl Acad Sci U S A. 1985 Apr;82(7):2188-91. doi: 10.1073/pnas.82.7.2188.

Properties of the apamin-sensitive Ca2+-activated K+ channel in PC12 pheochromocytoma cells which hyper-produce the apamin receptor.在超量产生蜂毒明肽受体的PC12嗜铬细胞瘤细胞中，蜂毒明肽敏感的Ca2+激活K+通道的特性

J Biol Chem. 1986 Jul 5;261(19):8633-7.

Dendrotoxin and charybdotoxin increase the cytosolic concentration of free Ca2+ in cerebrocortical synaptosomes: an effect not shared by apamin.树眼镜蛇毒素和蝎毒素可增加大脑皮质突触体中游离Ca2+的胞质浓度：这一效应是蜂毒明肽所没有的。

FEBS Lett. 1989 Sep 11;255(1):159-62. doi: 10.1016/0014-5793(89)81081-6.

引用本文的文献

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Protein Sci. 2023 Nov;32(11):e4776. doi: 10.1002/pro.4776.

Apamin structure and pharmacology revisited.蜂毒明肽的结构与药理学再探讨。

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Structural and Functional Diversity of Animal Toxins Interacting With GPCRs.与G蛋白偶联受体相互作用的动物毒素的结构与功能多样性

Front Mol Biosci. 2022 Feb 7;9:811365. doi: 10.3389/fmolb.2022.811365. eCollection 2022.

Idioventricular rhythm and shock after a honeybee sting.蜜蜂蜇伤后的心室自主节律与休克

Arch Cardiol Mex. 2021;91(2):186-189. doi: 10.24875/ACM.20000035.

Small and Intermediate Calcium Activated Potassium Channels in the Heart: Role and Strategies in the Treatment of Cardiovascular Diseases.心脏中的小电导和中电导钙激活钾通道：在心血管疾病治疗中的作用与策略

Front Physiol. 2020 Nov 23;11:590534. doi: 10.3389/fphys.2020.590534. eCollection 2020.

Therapeutic Effects of Apamin as a Bee Venom Component for Non-Neoplastic Disease.蜂毒组分蜂毒肽治疗非肿瘤性疾病的疗效。

Toxins (Basel). 2020 Mar 19;12(3):195. doi: 10.3390/toxins12030195.

Kalium 2.0, a comprehensive database of polypeptide ligands of potassium channels.钾离子通道多肽配体综合数据库 2.0（Kalium 2.0）

Sci Data. 2019 May 27;6(1):73. doi: 10.1038/s41597-019-0074-x.

Immunology of Bee Venom.蜂毒的免疫学。

Clin Rev Allergy Immunol. 2018 Jun;54(3):386-396. doi: 10.1007/s12016-017-8597-4.

Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan.三种来自蜜蜂和黄蜂毒液的、具有治疗和生物技术用途的珍贵肽：蜂毒肽、蜂毒明肽和马斯托帕兰。

Toxins (Basel). 2015 Apr 1;7(4):1126-50. doi: 10.3390/toxins7041126.

Apamin inhibits NO-induced relaxation of the spontaneous contractile activity of the myometrium from non-pregnant women.蜂毒明肽抑制一氧化氮诱导的非妊娠女性子宫肌层自发收缩活动的舒张。

Reprod Biol Endocrinol. 2003 Feb 5;1:8. doi: 10.1186/1477-7827-1-8.

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