Winship T R, Fong C K, Hsiung G D
J Gen Virol. 1984 Apr;65 ( Pt 4):843-7. doi: 10.1099/0022-1317-65-4-843.
Crude interferon preparations from primary guinea-pig embryo cells infected with vesicular stomatitis virus strain T1026R1 were shown to be more sensitive to heat (37 degrees C), pH 2.0, and SDS than crude mouse interferon. Since the proportion of antiviral activity lost after each treatment was nearly the same, the existence of a single fraction of antiviral activity sensitive to all three treatments was suggested. Support for this possibility was given by the finding that subjecting this guinea-pig interferon to any one of the treatments rendered it insensitive to the effects of the other two.
来自感染水疱性口炎病毒T1026R1株的原代豚鼠胚胎细胞的粗制干扰素制剂，相较于粗制小鼠干扰素，对热（37摄氏度）、pH 2.0和十二烷基硫酸钠（SDS）更为敏感。由于每次处理后丧失的抗病毒活性比例几乎相同，这表明存在单一部分对所有三种处理均敏感的抗病毒活性。对这一可能性的支持来自以下发现：对这种豚鼠干扰素进行任何一种处理后，它对其他两种处理的影响均不敏感。
